Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep77 | Adrenal and Cardiovascular Endocrinology | ECE2021

Hyperthermia differentially affects cortisol and aldosterone secretion under stimulated conditions

Donlon Padraig , Mullen Nathan , Warde Kate , Bottiglieri Anna , Cappiello Grazia , Farina Laura , Basel Matthew , Martin O’Halloran , Prakash Punit , Paula O’Shea , Dennedy Michael Conall

IntroductionPrimary Aldosteronism (PA) is the commonest secondary cause of hypertension. Mainstay therapy, adrenalectomy resects both hypersecreting and adjacent normal tissue. It is therefore only suitable for patients with unilateral disease (40% cases), whom are surgical candidates. Thermal therapy presents a plausible minimally invasive therapy, to target and disrupt hypersecreting aldosterone producing adenomas (APA), while also preserving adjacent ...